SURG-28. ADULT MIDLINE GLIOMAS TREATED WITH LASER INTERSTITIAL THERMAL THERAPY (LITT): OUR COMPARATIVE EXPERIENCE WITH NEEDLE BIOPSY

Abstract INTRODUCTION Adult midline gliomas are rare entities, with a scarcity of available clinical data. These patients have variable courses, limited evidence to predict outcomes. Emerging suggests that biomolecular profiles may play significant role in outcomes, so tissue diagnosis is key component management. However, the cytoreductive therapy, such as Laser Interstitial Thermal Therapy (LITT) remains unknown. To date, only few studies described use MRI-guided LITT for managing gliomas. OBJECTIVE present retrospective analysis single-center two-surgeon experience treating adult either biopsy/LITT or biopsy alone. METHODS Patients intraxial tumors surgically treated at our tertiary care referral center were identified using established database. Twenty-one managed needle from 2015 2021 included. Demographics and records including, among others, length hospital stay, preoperative lesion size, ablation volume, perioperative complications, adjuvant treatment, stratified overall survival (OS) collected. RESULTS The two cohorts composed 7 who underwent LITT, 14 biopsies. mean age was 60.95y (25-82). average tumor volumes 16.99 cm3 15.41 biopsy, respectively. No post-surgical complications found group, one patient had postsurgical hemorrhage after biopsy. OS 20.28 ± 9.63 months which greater but not statistically than group (11.05 4.45 months) (p = 0.605). CONCLUSION Our results show safe treatment gliomas, offer benefit given its properties.